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G, NY): fifty microliters of macrophages (100K cells) were mixed with 50 l of TiO2 (final conc. 50 g/ml) or fluorescent latex beads/bacteria (ratio of particles to cells: 50:1) and incubated at 37 for 40 min. Cells and particles were mixed once more during the assay at 20 min. In some assays, M were preincubated with scavenger receptor inhibitors, polyinosinic acid (Poly-I, 10 g/ml) and dextran

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