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Lum stress response pathway in Oikopleura but not human cells (Additional file 1, Figure S5B). It is not clear why Endoplasmic reticulum stress response pathway is responding more in Oikopleura. This pathway can be adaptive, promoting survival or it can lead to induction of apoptosis [39]. However, Apoptosis genes respond equally in both Oikopleura and the human macrophage cells (Additional file 1

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