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A showed only low sequence similarity to mouse proteins (BLASTP E-Yadetie et al. BMC Genomics 2012, 13:55 http://www.biomedcentral.com/1471-2164/13/Page 6 ofTable 1 Comparison of numbers of selected defensome genes in genomes of Oikopleura and other organismsGene AhR signaling CYP1 genes AhR AhRR ARNT Nuclear receptors NR1I (SXR/CAR/ VDR) NR1H (LXR/FXR) NR1C (PPAR) Nrf2-signaling Nrf2 Keap1 MafKaO

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