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Rly regulated, overexuberant response to infection so that levels of expression after infection often exceed those seen in WT mice. It is also of interest to note that several of the proteins (13 proteins out of 59) that were present in increased amounts in the uninfected SP-A-/- mice respond to infection by reducing their levelsAli et al. Proteome Science 2010, 8:34 http://www.proteomesci.com/co
Esenting the fact that expression is higher in SP-A-/- mice than in WT mice and indicating that in the SP-A-/- mice the synthesis and/or secretion of these proteins is rapidly enhanced by infection.3) Comparison of changes that occur in each strain between 4 and 24 hr after infectionA comparison of the infection-induced response between 4 and 24 hr in WT and SP-A-/- mice, was made by calculating
Esenting the fact that expression is higher in SP-A-/- mice than in WT mice and indicating that in the SP-A-/- mice the synthesis and/or secretion of these proteins is rapidly enhanced by infection.3) Comparison of changes that occur in each strain between 4 and 24 hr after infectionA comparison of the infection-induced response between 4 and 24 hr in WT and SP-A-/- mice, was made by calculating
Ovide [40] biological compatibility with less toxicity . According to the structural organizationOvide [40] biological compatibility with less toxicity . According to the structural organization, biodegradable nanoparticles are usually distinguished in nanospheres, where molecules are homogenously dispersed, adsorbed or dissolved within the polymeric matrix, and nanocapsules, where a polymer
Tatistically significant in WT mice, but did not achieve significance in the SP-A-/- mice. These proteins appear to play a role in asthma, chronic obstructive pulmonary disease, and other inflammatory lung diseases [37-39] although their exact action in these conditions is not known. Annexin A1 had a similar pattern, increasing with infection in both strains, but only reaching significance in the
Rger portion of the molecule for modeling, it was later suggested that a cationic loop region promoted nucleation by attracting Ca2+ ions, with the loop's flexibility allowing for rapid self-assembly with phosphate ions [130], rather than providing a regular template for crystallization. The flexible nature of the osteopontin structure when bound to the HA surface, was also predicted by molecular
Ex and exacerbating tooth decay. They have been associated with mutations in collagen in cases of osteogenesis imperfecta (OI) [136]. Defects in the human DSPP gene are the major cause of dentin disorders identified to date [137,138,139]. Mutations in DSPP are associated with five different types of inherited dentin defects ?dentinogenesis imperfecta (DGI) types I, II, III and dentinal dysplasias
Hemoglobin subunit alpha (Hemoglobin alpha chain) (Alpha-globin) Keratin complex 1, acidic, gene 10 Kpnb1 protein b Lactate dehydrogenase 2, B chain Murinoglobulin-1 presursor (MuG1) Myosin heavy chain IIB Peroxiredoxin 1 Prothrombin precursor (Ec 3.4.21.5) (Coagulation factor II) Pulmonary surfactant associated protein A precursor (SP-A) (PSP-A) (PSAP) Rho GDP dissociation inhibitor (GDI) alpha
Ice are shown for untreated (baseline) animals, 4 hours postinfection and 24 hours post-infection. Gel numbers (see Fig. 2), protein names, functional groups and percent change ( ) are listed. Abbreviations for functional groups: DEF, host defense; PMM, protein modification and metabolism; RED, redox regulation. Bolded numbers indicate changes that were significant (p
NPs can be made from many different polymer types including naturalNPs can be made from many different polymer types including natural or synthetic polymers such as poly-d,l-lactide-co-glycolide (PLGA), polylactic acid (PLA), poly--caprolactone (PCL), chitosan, gelatin, poly-alkyl-cyano-acrylates (PAC), gamma polyglutamic acid (-PGA), hyaluronan [or hyaluronic [34,35,39] acid (HA)] . However
WissProt accession numbers and percent change ( ) for both WT and SP-A-/- are listed. Bolded numbers indicate changes that were significant (p
WissProt accession numbers and percent change ( ) for both WT and SP-A-/- are listed. Bolded numbers indicate changes that were significant (p
The transformation to a crystalline phase and in others providing a means for remaining in an amorphous state. Some of these amorphous structures have short range order [117] and may be considered proto-crystalline [116]. For amorphous calcium carbonate, this short range order is only noted in the presence of additives, such as poly-aspartic acid. Since the amorphous structures aggregate to form
Esenting the fact that expression is higher in SP-A-/- mice than in WT mice and indicating that in the SP-A-/- mice the synthesis and/or secretion of these proteins is rapidly enhanced by infection.3) Comparison of changes that occur in each strain between 4 and 24 hr after infectionA comparison of the infection-induced response between 4 and 24 hr in WT and SP-A-/- mice, was made by calculating

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